Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer.

@article{Takahashi1995ExpressionOV,
  title={Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer.},
  author={Yoko Takahashi and Yasuhiko Kitadai and Corazon D. Bucana and Karen R. Cleary and Lee M. Ellis},
  journal={Cancer research},
  year={1995},
  volume={55 18},
  pages={3964-8}
}
We studied the correlation between expression of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and their receptors with vascularity, metastasis, and proliferative index of human colon cancers. Immunohistochemical analyses using antibodies against VEGF, bFGF, their receptors (KDR, flt-1, bek, and flg), factor VIII, and proliferating cell nuclear antigen were carried out on archival specimens of 52 human colon carcinomas and 10 adenomas. Vessels were… CONTINUE READING
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