Expression of vascular endothelial growth factor and its receptors in inflamed and vascularized human corneas.

@article{Philipp2000ExpressionOV,
  title={Expression of vascular endothelial growth factor and its receptors in inflamed and vascularized human corneas.},
  author={Wolfgang E Philipp and Lilly Speicher and Christian Humpel},
  journal={Investigative ophthalmology & visual science},
  year={2000},
  volume={41 9},
  pages={
          2514-22
        }
}
PURPOSE To help further define the possible role of vascular endothelial growth factor (VEGF) in the pathogenesis of corneal neovascularization, the expression of VEGF and of its receptors Flt-1 and Flk-1 was investigated in various inflammatory corneal diseases. METHODS Polyclonal antibodies to VEGF and its receptors were used for immunohistochemical staining of frozen sections of 38 human corneas with various degrees of neovascularization and inflammation. In addition, a panel of monoclonal… CONTINUE READING
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