Expression of vascular endothelial growth factor in capillary hemangioblastoma.

  title={Expression of vascular endothelial growth factor in capillary hemangioblastoma.},
  author={Ken Morii and Rie Tanaka and Kazuo Washiyama and Toshiro Kumanishi and Ryozo Kuwano},
  journal={Biochemical and biophysical research communications},
  volume={194 2},
The gene expression of vascular endothelial growth factor (VEGF), an endothelial cell-specific mitogen, was examined in capillary hemangioblastomas which are composed of abundant microvasculature and primitive angiogenic elements represented by stromal cells. Northern blot and in situ hybridization analyses showed that the VEGF mRNA was highly expressed in the stromal cells, but not in the endothelial cells. Reverse transcription/PCR analysis revealed that the VEGF mRNA species expressed in the… CONTINUE READING
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