Expression of various TGF-β isoforms and type I receptor in necrotizing human brain lesions

@article{Ata1997ExpressionOV,
  title={Expression of various TGF-β isoforms and type I receptor in necrotizing human brain lesions},
  author={Athar Ata and Keiko Funa and Yngve Olsson},
  journal={Acta Neuropathologica},
  year={1997},
  volume={93},
  pages={326-333}
}
It is known that transforming growth factor beta (TGF-β) is involved in the modulation of cell growth, differentiation, and repair following injury. We performed an immunohistochemical study of human brain autopsy and biopsy material for the expression of TGF-β isoforms β1, β2 and β3, and TGF-β receptor (TβR) type I in different cells of necrotizing lesions such as infarction and abscess, and compared them with controls. Various cell types, both inside and in the proximity of lesions, showed… CONTINUE READING

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