Expression of urease by Haemophilus influenzae during human respiratory tract infection and role in survival in an acid environment

@inproceedings{Murphy2011ExpressionOU,
  title={Expression of urease by Haemophilus influenzae during human respiratory tract infection and role in survival in an acid environment},
  author={Timothy F. Murphy and Aimee L. Brauer},
  booktitle={BMC Microbiology},
  year={2011}
}
Nontypeable Haemophilus influenzae is a common cause of otitis media in children and lower respiratory tract infection in adults with chronic obstructive pulmonary disease (COPD). Prior studies have shown that H. influenzae expresses abundant urease during growth in the middle ear of the chinchilla and in pooled human sputum, suggesting that expression of urease is important for colonization and infection in the hostile environments of the middle ear and in the airways in adults. Virtually… CONTINUE READING
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