Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and nonreciprocal cross competition by acetylated and oxidized low density lipoprotein.

@article{Freeman1991ExpressionOT,
  title={Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and nonreciprocal cross competition by acetylated and oxidized low density lipoprotein.},
  author={Mason Wright Freeman and Y Ekkel and Lucia Rohrer and Marsha L Penman and Neil J. Freedman and Guy M. Chisolm and Monty Krieger},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1991},
  volume={88 11},
  pages={4931-5}
}
Type I and type II scavenger receptors, which have been implicated in the development of atherosclerosis and other macrophage-associated functions, differ only by the presence in the type I receptor of an extracellular cysteine-rich C-terminal domain. Stable Chinese hamster ovary (CHO) cell transfectants expressing high levels of either the type I or type II bovine scavenger receptors have been generated. Type I and type II receptors in these cells mediated high-affinity saturable endocytosis… CONTINUE READING

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