Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

@article{Sassoon1989ExpressionOT,
  title={Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis},
  author={D. M. B. Sassoon and Gary Lyons and Woodring E Wright and Victor Guosheng Lin and Andrew B. Lassar and Harold Weintraub and M. Buckingham},
  journal={Nature},
  year={1989},
  volume={341},
  pages={303-307}
}
MyoDl and myogenin are muscle-specific proteins which can convert non-myogenic cells in culture to differentiated muscle fibres, implicating them in myogenic determination. The pattern of expression of MyoDl and myogenin during the early stages of muscle formation in the mouse embryo in vivo and in limb-bud explants cultured in vitro, indicates that they may have different functions in different types of muscle during development. 
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