Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma.

@article{Roncador2007ExpressionOT,
  title={Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma.},
  author={Giovanna Roncador and Jos{\'e}-Francisco Garc{\'i}a Verdes-Montenegro and Sara Tedoldi and Jennifer C. Paterson and Wolfram Klapper and Erica Ballabio and Lorena Maestre and Stefano A Pileri and Martin-Leo Hansmann and Miguel {\'A}ngel Piris and David Mason and Teresa Marafioti},
  journal={Haematologica},
  year={2007},
  volume={92 8},
  pages={1059-66}
}
BACKGROUND AND OBJECTIVES In the present paper we report that SAP, an intracytoplasmic molecule that is involved in cell signaling, is an immunohistologic marker for germinal center T cells in paraffin-embedded tissue. We document its expression, and also that of PD-1 (another recently described marker of germinal center T cells to which a new antibody has been raised), in normal and neoplastic lymphoid tissue to evaluate the suggestion that helper T cells within the germinal centers of human… CONTINUE READING

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