Expression of tumor necrosis factor-stimulated gene-6 in the rat ovary in response to an ovulatory dose of gonadotropin.

@article{Yoshioka2000ExpressionOT,
  title={Expression of tumor necrosis factor-stimulated gene-6 in the rat ovary in response to an ovulatory dose of gonadotropin.},
  author={Shinya Yoshioka and Scott D. Ochsner and Darryl Lyndon Russell and Takeshi Ujioka and Shunsaku Fujii and Joanne S. Richards and Lawrence L. Espey},
  journal={Endocrinology},
  year={2000},
  volume={141 11},
  pages={
          4114-9
        }
}
Current evidence supports the hypothesis that the biochemical events of mammalian ovulation are analogous to an acute inflammatory reaction. This study reveals that tumor necrosis factor-stimulated gene-6 (TSG-6), which encodes a member of the superfamily of hyaluronan-binding proteins that is specifically translated in inflammatory reactions, is expressed in ovarian follicles that have been induced to ovulate. Immature Wistar rats were primed with 10 IU equine CG s.c.; and 48 h later, the 12-h… CONTINUE READING
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6 that is specifically expressed by expanding cumulus cell - oocyte complexes

  • LL Espey, S Yoshioka, +6 authors JS Richards
  • 2000

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