Expression of transforming growth factor alpha in human gliomas.

@article{Schlegel1990ExpressionOT,
  title={Expression of transforming growth factor alpha in human gliomas.},
  author={Uwe Schlegel and Paul L. Moots and Marc K. Rosenblum and Howard T. Thaler and Henry M. Furneaux},
  journal={Oncogene},
  year={1990},
  volume={5 12},
  pages={1839-42}
}
Expression of transforming growth factor alpha (TGF alpha) is frequently associated with the development of human and animal tumors. Using a sensitive immunohistochemical assay, which can be applied on formalin-fixed, paraffin-embedded tissue, we have examined the expression of TGF alpha in 71 human gliomas (63 untreated and 8 recurrent tumors). Tumors were graded by a 3-grade-system: grade I = low grade gliomas, grade II = anaplastic gliomas and grade III = glioblastomas. A strong positive… CONTINUE READING