Expression of transforming growth factor-β receptor type II gene in gastric cancer cell lines


Multiple genetic changes including activation of proto-oncogenes and inactivation of tumor suppressor genes occur during gastric carcinogenesis. Several receptor tyrosine kinases such as K-sam, c-erbB2 and c-met are amplified frequently in gastric cancer (1). K-sam gene and c-erbB3 gene encode secreted as well as transmembrane receptor tyrosine kinase (2, 3… (More)
DOI: 10.1007/BF02806358


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