Expression of topoisomerase II-α in triple negative breast cancer.

@article{Mrkli2014ExpressionOT,
  title={Expression of topoisomerase II-α in triple negative breast cancer.},
  author={Ivana Mrkli{\'c} and Zenon Pogoreli{\'c} and Vesna {\vC}apkun and Snjezana D Tomi{\'c}},
  journal={Applied immunohistochemistry & molecular morphology : AIMM},
  year={2014},
  volume={22 3},
  pages={182-7}
}
Triple negative breast cancer (TNBC)-defined by estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 negativity is a group with poor prognosis, due to aggressive tumor biology and lack of targeted therapy. Topoisomerase II-α (topoIIα) protein is one of the intracellular targets for anthracycline-based therapy, and high levels of topoIIα expression are recently observed in TNBC. The study included 83 patients who underwent surgery between January 2003 and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…