Expression of tissue factor procoagulant activity: regulation by cytosolic calcium.

@article{Bach1990ExpressionOT,
  title={Expression of tissue factor procoagulant activity: regulation by cytosolic calcium.},
  author={Ronald R. Bach and Daniel B. Rifkin},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1990},
  volume={87 18},
  pages={6995-9}
}
Intact bovine fibroblasts, pericytes, and kidney cells manifested significantly less tissue factor procoagulant activity than their disrupted counterparts. Addition of calcium ionophore A23187 rapidly and reversibly enhanced the cell-surface expression of tissue factor in intact cells up to the level achieved by disruption. Inhibitors of calmodulin blocked… CONTINUE READING