Expression of the vasopressin and oxytocin genes in rats occurs in mutually exclusive sets of hypothalamic neurons.

@article{Mohr1988ExpressionOT,
  title={Expression of the vasopressin and oxytocin genes in rats occurs in mutually exclusive sets of hypothalamic neurons.},
  author={Evita Mohr and Ulrich Bahnsen and Corinna Kiessling and D. F. E. Richter},
  journal={FEBS letters},
  year={1988},
  volume={242 1},
  pages={144-8}
}
The genes for the hypothalamic hormones vasopressin and oxytocin are located in close proximity to each other within the rat genome. They are separated by only approx. 11 kbp of DNA sequence and oriented in such a way that their transcription occurs on opposite DNA strands. Although the two genes are structurally very similar including common potential regulatory elements in their putative promotor regions, they are expressed in discrete populations of magnocellular neurons of the hypothalamus… CONTINUE READING

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