Expression of the surface glycoprotein E2 of Bovine viral diarrhea virus by recombinant vesicular stomatitis virus.

@article{Khl2007ExpressionOT,
  title={Expression of the surface glycoprotein E2 of Bovine viral diarrhea virus by recombinant vesicular stomatitis virus.},
  author={Wiebke K{\"o}hl and Andrea Gr{\"o}ne and Volker Moennig and Georg Herrler},
  journal={The Journal of general virology},
  year={2007},
  volume={88 Pt 1},
  pages={157-65}
}
This study analysed the transport behaviour of the glycoprotein E2 of Bovine viral diarrhea virus (BVDV) expressed from recombinant vesicular stomatitis virus (rVSV). E2 protein was found to be retained at an intracellular compartment. A chimeric protein containing the membrane anchor and cytoplasmic tail of the VSV G protein, E2-G(MT), was transported to the cell surface. Only the latter protein was incorporated into rVSV particles in significant amounts. A soluble form of E2 lacking the… CONTINUE READING