Expression of the steroidogenic acute regulatory (StAR) protein: a novel LH-induced mitochondrial protein required for the acute regulation of steroidogenesis in mouse Leydig tumor cells.

Abstract

The acute response of steroidogenic cells to hormone stimulation is the mobilization of cholesterol from cellular stores and the outer mitochondrial membrane to the inner mitochondrial membrane and the cholesterol side-chain cleavage complex (CSCC) where the first enzymatic reaction occurs. It has been well established that the translocation of cholesterol… (More)

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