Expression of the sonic hedgehog gene in human embryos with neural tube defects.

Abstract

BACKGROUND To estimate the rate of malformations observed during early human development, a series of 38,913 first-trimester abortions were studied. Neural tube defects (NTD) were found in 57 cases. METHODS A histological study of serial sections performed in 25 embryos revealed a spectrum of axial structure abnormalities. Expression of the SHH gene was… (More)

Topics

  • Presentations referencing similar topics