Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer

Abstract

Despite the near universal occurrence of activating codon 12 KRAS somatic variants in pancreatic cancer, there is considerable heterogeneity in the molecular make-up, MAPK/ERK pathway activation states, and clinical outcome in this disease. We analyzed the expression levels of CNKSR1, a scaffold that influences MAPK/ERK pathway activity, in clinical… (More)
DOI: 10.1186/s12885-017-3481-4

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Cite this paper

@inproceedings{Quadri2017ExpressionOT, title={Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer}, author={Humair S. Quadri and Taylor J. Aiken and Michael Allgaeuer and Radim Moravec and Sean F. Altekruse and S. Perwez Hussain and Markku Miettinen and Stephen M. Hewitt and Udo Rudloff}, booktitle={BMC Cancer}, year={2017} }