Expression of the relaxin gene in rat tissues.

  title={Expression of the relaxin gene in rat tissues.},
  author={Jenny Margaret Gunnersen and Robert J. Crawford and Geoffrey W. Tregear},
  journal={Molecular and cellular endocrinology},
  volume={110 1-2},
The peptide hormone relaxin is produced at high levels in the corpus luteum of the rat ovary during pregnancy. The biological effects of the hormone include remodelling of collagen in target tissues such as the cervix, and inhibition of uterine contractility. In addition, many paracrine actions for the hormone have been proposed, however sites of relaxin production outside the ovary have not been well characterized. We have investigated relaxin gene expression in a range of rat tissues using… CONTINUE READING
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