Expression of the rat homologue of the Drosophila fat tumour suppressor gene

@article{Ponassi1999ExpressionOT,
  title={Expression of the rat homologue of the Drosophila fat tumour suppressor gene},
  author={Marco Ponassi and Thomas S Jacques and Lorenza Ciani and Charles ffrench-Constant},
  journal={Mechanisms of Development},
  year={1999},
  volume={80},
  pages={207-212}
}
We have sequenced and defined the expression during rat embryogenesis of the protocadherin fat, the murine homologue of a Drosophila tumour suppressor gene. As previously described for human fat, the sequence encodes a large protocadherin with 34 cadherin repeats, five epidermal growth factor (EGF)-like repeats containing a single laminin A-G domain and a putative transmembrane portion followed by a cytoplasmic sequence. This cytoplasmic sequence shows homology to the b-catenin binding regions… CONTINUE READING

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