Expression of the platelet-derived growth factor beta receptor during organogenesis and tissue differentiation in the mouse embryo.

@article{Shinbrot1994ExpressionOT,
  title={Expression of the platelet-derived growth factor beta receptor during organogenesis and tissue differentiation in the mouse embryo.},
  author={E Shinbrot and Kevin G. Peters and Lewis T. Williams},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={1994},
  volume={199 3},
  pages={169-75}
}
In this study we used in situ hybridization to localize expression of the platelet-derived growth factor beta (PDGF beta) receptor mRNA during organogenesis in the mouse embryo (E 9.5-16.5). Expression was first seen in periaortic mesenchyme (E 9.5-10.5). Later (E 12.5-E 16.5), the receptor was expressed in the mesenchymal component of many developing tissues and organs, particularly derivatives of the primitive gut. The expression was exceptionally high in mesenchyme directly supporting an… CONTINUE READING
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