Expression of the p63 and Notch signaling systems in rat testes during postnatal development: comparison with their expression levels in the epididymis and vas deferens.

@article{Hayashi2004ExpressionOT,
  title={Expression of the p63 and Notch signaling systems in rat testes during postnatal development: comparison with their expression levels in the epididymis and vas deferens.},
  author={Tetsuo Hayashi and Atsushi Yoshinaga and Rena Ohno and Nobuyuki Ishii and Shigeyoshi Kamata and Takumi Yamada},
  journal={Journal of andrology},
  year={2004},
  volume={25 5},
  pages={692-8}
}
The role of tubular structures that contribute to the passage of spermatozoa is not solely passive; these structures actively contribute to their own functions, although these tubules and ducts are contiguous and collaborate in the development of the male gamete along their lengths. The testis has the specific function to generate spermatozoa and spermatozoa undergo numerous changes as they pass through the epididymis. A member of the p53 family of genes, p63, is highly expressed in the basal… CONTINUE READING

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Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
EpididymisDirect continuous withVas deferens structure
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
Vas deferens structureDirect continuous withEpididymis
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
Expression of the p63 and Notch signaling systems in rat testes during postnatal development : comparison with their expression levels in the epididymis and vas deferens .
On the other hand , the strong signal of DeltaNp63 mRNA was already recognized in the vas deferens at day 0 after birth and advanced chronologically along the duct to the caput epididymis and p63 protein was expressed in basal cells in their epithelium , whereas the mRNAs of Jagged 2 and Notch 1 were maintained at a low level .
ApoptosisProcess involves geneNOTCH1 gene
A member of the p53 family of genes , p63 , is highly expressed in the basal layers of epithelial tissues and plays a key role in maintaining their cell populations , whereas Notch 1 and its ligand Jagged 2 have an important role in the differentiation of germ cells and Jagged 2 is up - regulated by TAp63 , one of the p63 isoforms , which transactivates p53 target genes and induces apoptosis .
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