Expression of the p53 tumour suppressor gene as a prognostic marker in platinum-treated patients with ovarian cancer.

@article{Marx1998ExpressionOT,
  title={Expression of the p53 tumour suppressor gene as a prognostic marker in platinum-treated patients with ovarian cancer.},
  author={Dagmar Marx and Harald Meden and T Ziemek and T Lenthe and Walther Christian Kuhn and Alfred Schauer},
  journal={European journal of cancer},
  year={1998},
  volume={34 6},
  pages={845-50}
}
Drug resistance is one of the most important clinical problems in the treatment of ovarian cancer. This study was designed to determine whether expression of p53 could be used as a marker for predicting the response to chemotherapy of ovarian cancer. Tissue blocks were obtained from 187 patients with diagnosed untreated ovarian cancer. Paraffin sections… CONTINUE READING