Expression of the nmpC gene of Escherichia coli K-12 is modulated by external pH. Identification of cis-acting regulatory sequences involved in this regulation.

@article{Coll1994ExpressionOT,
  title={Expression of the nmpC gene of Escherichia coli K-12 is modulated by external pH. Identification of cis-acting regulatory sequences involved in this regulation.},
  author={Julio Coll and M. Meyer zur Heyde and Raymond C. Portalier},
  journal={Molecular microbiology},
  year={1994},
  volume={12 1},
  pages={83-93}
}
Using a set of gene fusions generated with TnphoA, we previously identified the phmA locus, whose expression is modulated as a function of external pH (pHo). The phmA::phoA fusion was cloned and sequenced and the phmA locus was identified with the nmpC gene. This gene lies within the defective lambdoid prophage qsr' and NmpC is an outer membrane protein which functions as a porin. We demonstrated that nmpC is sensitive to catabolite repression and dependent on the CRP-cAMP complex. However… CONTINUE READING