Expression of the neuropeptide Y Y1 receptor in the CNS of rat and of wild-type and Y1 receptor knock-out mice. Focus on immunohistochemical localization.

@article{Kopp2002ExpressionOT,
  title={Expression of the neuropeptide Y Y1 receptor in the CNS of rat and of wild-type and Y1 receptor knock-out mice. Focus on immunohistochemical localization.},
  author={Jutta Kopp and Z e Q i Xu and X Zhang and Thierry Pedrazzini and Herbert Herzog and Adelheid Kresse and Helen Wong and John H. Walsh and Tomas G M H{\"o}kfelt},
  journal={Neuroscience},
  year={2002},
  volume={111 3},
  pages={443-532}
}
The distribution of neuropeptide Y (NPY) Y1 receptor-like immunoreactivity (Y1R-LI) has been studied in detail in the CNS of rat using a rabbit polyclonal antibody against the C-terminal 13 amino acids of the rat receptor protein. The indirect immunofluorescence technique with tyramide signal amplification has been employed. For specificity and comparative reasons Y1 knock-out mice and wild-type controls were analyzed. The distribution of Y1R mRNA was also studied using in situ hybridization. A… CONTINUE READING

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