Expression of the multidrug resistance glycoprotein 170 in the peripheral blood lymphocytes of rheumatoid arthritis patients. The percentage of lymphocytes expressing glycoprotein 170 is increased in patients treated with prednisolone.

@article{Maillefert1996ExpressionOT,
  title={Expression of the multidrug resistance glycoprotein 170 in the peripheral blood lymphocytes of rheumatoid arthritis patients. The percentage of lymphocytes expressing glycoprotein 170 is increased in patients treated with prednisolone.},
  author={J. F. Maillefert and Marck Maynadi{\'e} and Jacques Guy Tebib and Serge Ludwig Aho and Phyllis S. Walker and C Chatard and V{\'e}ronique Dulieu and Michel Bouvier and Paule Marie Carli and Christian G Tavernier},
  journal={British journal of rheumatology},
  year={1996},
  volume={35 5},
  pages={430-5}
}
The objective was to evaluate the expression of the multidrug resistance P-glycoprotein (P-gp) in peripheral blood lymphocytes (PBL) of patients with rheumatoid arthritis (RA). PBL from 68 RA patients and 44 controls were evaluated. RA patients had a mean disease duration of 10.7 yr, with a mean number of past resistances to DMARDs of 0.82, and were treated with NSAIDs (n = 34), DMARDs (n = 25) and prednisolone (n = 40). Fluorescence flow cytometry was used to assess P-gp membrane expression on… CONTINUE READING
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