Expression of the mitochondrial creatine kinase genes

  title={Expression of the mitochondrial creatine kinase genes},
  author={Ronald M Payne and Arnold W. Strauss},
  journal={Molecular and Cellular Biochemistry},
Mitochondrial Creatine Kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine, and exists in mammals as two isoenzymes encoded by separate genes. In rats and humans, sarcomere-specific MtCK (sMtCK) is expressed only in skeletal and heart muscle, and has 87% nucleotide identity across the… CONTINUE READING