Expression of the mammalian calcium signaling response to Trypanosoma cruzi in Xenopus laevis oocytes.

@article{Leite1998ExpressionOT,
  title={Expression of the mammalian calcium signaling response to Trypanosoma cruzi in Xenopus laevis oocytes.},
  author={Maria Fernanda Leite and M Susan Moyer and Norma W Andrews},
  journal={Molecular and biochemical parasitology},
  year={1998},
  volume={92 1},
  pages={1-13}
}
Infective stages of the protozoan parasite Trypanosoma cruzi contain a soluble factor that induces elevation in the intracellular free Ca2+ concentration ([Ca2+]i) of mammalian cells. The process is pertussis toxin (PTx)-sensitive, and involves phospholipase C (PLC) activation, inositol 1,4,5-trisphosphate (IP3) formation and Ca2+ release from intracellular stores (Tardieux I, et al. J Exp Med 1994;179:1017-1022; Rodriguez A, et al. J Cell Biol 1995;129:1263-1273). We now report that a molecule… CONTINUE READING
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