Expression of the mRNAs for the insulin-like growth factors and their binding proteins during development of porcine ovarian follicles.

@article{Samaras1993ExpressionOT,
  title={Expression of the mRNAs for the insulin-like growth factors and their binding proteins during development of porcine ovarian follicles.},
  author={Susan E. Samaras and H. David Guthrie and Jeremy A Barber and James M. Hammond},
  journal={Endocrinology},
  year={1993},
  volume={133 5},
  pages={2395-8}
}
We examined the expression of the mRNAs for the insulin-like growth factors (IGFs) and two of their binding proteins (BPs), IGFBP-2 and IGFBP-3, in individual follicles of the porcine ovary. Follicular development was synchronized with a progestin (altrenogest). Individual follicles were isolated on days 1, 3, 5 and 7 after progestin withdrawal. No IGFBP-3 mRNA was detected. While IGF-II mRNA was easily detected, the levels of expression did not change. IGF-I and IGFBP-2 mRNAs increased and… CONTINUE READING

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