Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol.

@article{Mukherjee2009ExpressionOT,
  title={Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol.},
  author={Subhendu Mukherjee and Istvan Lekli and Narasimman Gurusamy and Alberto A. E. Bertelli and Dipak Kumar Das},
  journal={Free radical biology & medicine},
  year={2009},
  volume={46 5},
  pages={573-8}
}
Resveratrol increases longevity through SirT1, which is activated with NAD(+) supplied by an anti-aging enzyme PBEF. SirT1 interacts with an anti-aging transcription factor, FoxO1, which is negatively regulated by Akt. Since white wine could have similar health benefits as red wine, we determined if white wine and its cardioprotective components possess anti-aging properties by feeding rats with these compounds. The hearts expressed SirT, FoxO, and PBEF in the order of white wine>resveratrol… CONTINUE READING

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