Expression of the full-length form of gp2 of equine herpesvirus 1 (EHV-1) completely restores respiratory virulence to the attenuated EHV-1 strain KyA in CBA mice.

@article{Smith2005ExpressionOT,
  title={Expression of the full-length form of gp2 of equine herpesvirus 1 (EHV-1) completely restores respiratory virulence to the attenuated EHV-1 strain KyA in CBA mice.},
  author={Patrick M. Smith and Shannon M Kahan and Colin B. Rorex and Jens von Einem and Nikolaus Osterrieder and D J O'callaghan},
  journal={Journal of virology},
  year={2005},
  volume={79 8},
  pages={5105-15}
}
Wild-type equine herpesvirus 1 (EHV-1) strains express a large (250-kDa) glycoprotein, gp2, that is encoded by EUs4 (gene 71) located within the unique short region of the genome. DNA sequence analysis revealed that EUs4 of the pathogenic EHV-1 strain RacL11 is an open reading frame of 2,376 bp that encodes a protein of 791 amino acids. The attenuated EHV-1… CONTINUE READING