Expression of the extracellular matrix metalloproteinase inducer (EMMPRIN) and the matrix metalloproteinase-2 in bronchopulmonary and breast lesions.

@article{Caudroy1999ExpressionOT,
  title={Expression of the extracellular matrix metalloproteinase inducer (EMMPRIN) and the matrix metalloproteinase-2 in bronchopulmonary and breast lesions.},
  author={St{\'e}phanie Caudroy and Myriam Polette and Jean Marie Tournier and Henriette Burlet and Bryan P. Toole and Stanley Zucker and Philippe Birembaut},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={1999},
  volume={47 12},
  pages={1575-80}
}
Tumor cells interact with stromal cells via soluble or cell-bound factors stimulating the production of matrix metalloproteinases (MMPs), a group of enzymes largely involved in the extracellular matrix (ECM) remodeling in tumor invasion. Among these factors, extracellular matrix metalloproteinase inducer (EMMPRIN) has been shown to stimulate in vitro the fibroblast production of various MMPs such as interstitial collagenase (MMP-1), stromelysin-1 (MMP-3), and gelatinase A (MMP-2). In this study… CONTINUE READING
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