Expression of the components and regulatory proteins of the alternative complement pathway and the membrane attack complex in normal and diseased synovium

@article{Guc1993ExpressionOT,
  title={Expression of the components and regulatory proteins of the alternative complement pathway and the membrane attack complex in normal and diseased synovium},
  author={Dicle Guc and P. Gulati and C. Lemercier and D. Lappin and George D. Birnie and K. Brigitta Whaley},
  journal={Rheumatology International},
  year={1993},
  volume={13},
  pages={139-146}
}
We have studied synthesis of the complement components and regulatory proteins of the alternative pathway and the membrane attack complex in synovial membrane. RNA was extracted from synovial tissue of patients with rheumatoid arthritis (RA) or osteoarthritis (OA) as well as from normal synovial membrane. Dot blot analysis showed the presence of mRNAs for all the complement components and regulatory proteins (C3, factor B, factor D, C5, C6, C7, C9, factor H, factor I, S-protein, SP-40, 40, DAF… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 40 references

Cellular responses to the membrane attack complex

  • BP Morgan
  • Wailer J (ads) Complement in health and disease,
  • 1993
2 Excerpts

Complement receptors

  • Law SKA
  • 1993

Synthesis of complement components and at extrahepatic sites

  • RC Colten HR Struck
  • Wailer J (eds) Complement in health and disease,
  • 1993
2 Excerpts

Rheumatoid arthritis , cell and tissue pathology

  • DL Gardner
  • 1992

Rheumatoid arthritis, cell and tissue pathology. In: Gardner DL (ed) Pathological basis of connective tissue disease

  • DL Gardner
  • 1992
1 Excerpt

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