Expression of the breast differentiation antigen NY-BR-1 in a phyllodes tumor of the vulva

@article{Giger2007ExpressionOT,
  title={Expression of the breast differentiation antigen NY-BR-1 in a phyllodes tumor of the vulva},
  author={Olivier T. Giger and Elena Lacoste and Christoph Honegger and Barbara -Christina Padberg and Holger Moch and Zsuzsanna Varga},
  journal={Virchows Archiv},
  year={2007},
  volume={450},
  pages={471-474}
}
We describe a phyllodes tumor of borderline malignancy in the labium majus of a 49-year-old woman. The histogenetic origin of phyllodes tumors in the vulva is controversial. Strong immunoreactivity for NY-BR-1, a novel breast differentiation antigen, was demonstrated within the epithelial components of the phyllodes tumor. A similar expression pattern was observed in mammary-like glands of the vulva. These findings provide further evidence that phyllodes tumors of the vulva might derive from… CONTINUE READING

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