Expression of the SART1 tumor-rejection antigens in colorectal cancers.

  title={Expression of the SART1 tumor-rejection antigens in colorectal cancers.},
  author={Teruo Sasatomi and Hideaki Yamana and Shigeki Shichijo and Shu Tanaka and Torahiko Okamura and Yutaka Ogata and Kyogo Itoh and Kazuo Shirouzu},
  journal={Diseases of the colon and rectum},
  volume={43 12},
PURPOSE Colorectal cancer is one of the major causes of cancer death in the world, including in the United States and Japan. We recently identified the tumor-rejection antigen gene SART1, which encodes both the SART1(259) antigen expressed in the cytosol of epithelial cancers and the SART1(800) antigen expressed in the nucleus of the majority of proliferating cells. This study investigated the expression of these tumor antigens to explore a potential molecule for specific immunotherapy of… CONTINUE READING