Expression of the Na+-K+-2Cl- cotransporter in the rat endolymphatic sac.


The endolymphatic sac (ES) is a part of the membranous labyrinth that contains the cochlea, vestibular organs, an d semicircular canals, and is believed to absorb endolymphatic fluid. Na(+)-K(+)-2Cl(-) (NKCC) is a cotransporter that occurs as two isoforms (NKCC-1 and NKCC-2). Especially, NKCC-2 is suggested to participate in ES endolymph absorption. In the… (More)
DOI: 10.1016/j.bbrc.2007.10.107


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