Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction.

@article{Pende2006ExpressionOT,
  title={Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction.},
  author={Daniela Pende and Roberta Castriconi and Paola Romagnani and Grazia Maria Spaggiari and Stefania Marcenaro and Alessandra Dondero and Elena Lazzeri and Laura Lasagni and Stefania Martini and Paola X Rivera and Andrea Capobianco and Alessandro Moretta and Cristina Bottino},
  journal={Blood},
  year={2006},
  volume={107 5},
  pages={2030-6}
}
In this study, we demonstrate the involvement of DNAM-1-triggering receptor and its ligands, poliovirus receptor (PVR) and Nectin-2, in natural killer (NK) cell-mediated lysis of dendritic cells (DCs). The surface expression of both ligands was up-regulated in DCs as compared to monocytes. It reached maximal densities after DC maturation induced by different stimuli including lipopolysaccharide (LPS), poly I:C, flagellin, and CD40L. Both immunohistochemical analysis and confocal microscopy… CONTINUE READING
89 Citations
38 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 89 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

NK cellmediated lysis of autologous antigen presenting NECTIN-2 AND PVR EXPRESSION ON DCs 2035 BLOOD, 1 MARCH

  • GM Spaggiari, R Carosio, D Pende
  • For personal use only. on April
  • 2006

NK-dependent maturation is mediated by TNF and IFN released upon engagement of the NKp30 triggering receptor

  • M Vitale, M Della Chiesa, S Carlomagno
  • Blood
  • 2005

DNAM-1 and PVR act as regulators of monocytes migration through endothelial junctions

  • N Reymond, A-M Imbert, E Devilard
  • J Exp Med
  • 2004

Similar Papers

Loading similar papers…