Expression of the D-MEF2 transcription in the Drosophila brain suggests a role in neuronal cell differentiation.

@article{Schulz1996ExpressionOT,
  title={Expression of the D-MEF2 transcription in the Drosophila brain suggests a role in neuronal cell differentiation.},
  author={Robert A Schulz and Caroline Chromey and Mei Fang Lu and Bryan Zhao and Eric N Olson},
  journal={Oncogene},
  year={1996},
  volume={12 8},
  pages={1827-31}
}
D-MEF2 is a MADS domain transcription factor expressed in the cardiac, somatic, and visceral muscle cell lineages in the Drosophila embryo. Genetic studies have demonstrated that D-mef2 gene function is required for the proper differentiation of all three of these muscle types. We show that D-MEF2 is also expressed in a limited number of other cells types during development, including Kenyon cells present in the mushroom bodies of the Drosophila brain. This finding suggests a role for D-mef2 in… CONTINUE READING