Expression of the CD34 antigen in pleomorphic xanthoastrocytomas

  title={Expression of the CD34 antigen in pleomorphic xanthoastrocytomas},
  author={Guido Reifenberger and Kerstin Kaulich and Otmar Dieter Wiestler and Ingmar Bl{\"u}mcke},
  journal={Acta Neuropathologica},
Pleomorphic xanthoastrocytoma (PXA) is a rare, superficially located astrocytic glioma of children and young adults, which is associated with a relatively favorable prognosis. Here we report on the expression of the hematopoietic progenitor cell and vascular endothelial cell associated antigen CD34 in PXAs. We found CD34 immunoreactivity in various fractions of tumor cells in 44 of 60 PXAs investigated (73%). CD34 expression was more common in PXAs of WHO grade II (37 of 44 tumors, 84%) than… CONTINUE READING
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Pleomor - phic xanthoastrocytoma

  • JJ Kepes, DN Louis, C Giannini, W Paulus
  • World Health Organization classification of…
  • 2000

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