Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes.

@article{Veis1993ExpressionOT,
  title={Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes.},
  author={D J Veis and Charles L. Sentman and Erika A Bach and S Stanley J. Korsmeyer},
  journal={Journal of immunology},
  year={1993},
  volume={151 5},
  pages={2546-54}
}
Bcl-2, a proto-oncogene that can block apoptosis, was found to be expressed throughout the thymic medulla, but in only scattered cells in the thymic cortex. In order to determine the precise distribution of Bcl-2 protein during thymocyte development, we utilized mAb specific for either mouse or human Bcl-2. Thymocyte subpopulations were assessed using three… CONTINUE READING