Expression of the ADP/ATP carrier and expansion of the mitochondrial (ATP + ADP) pool contribute to postnatal maturation of the rat heart.

@article{Schnfeld1996ExpressionOT,
  title={Expression of the ADP/ATP carrier and expansion of the mitochondrial (ATP + ADP) pool contribute to postnatal maturation of the rat heart.},
  author={Peter Sch{\"o}nfeld and Lorenz Schild and Ralf Bohnensack},
  journal={European journal of biochemistry},
  year={1996},
  volume={241 3},
  pages={
          895-900
        }
}
The role of the ADP/ATP carrier (AAC), a key protein of the mitochondrial ATP-generating system, is not clear during postnatal rat heart development. To elucidate this role, the phosphorylating respiration (state 3), the activity and the content of AAC, the size of the exchangeable mitochondrial (ATP + ADP) pool and the control of AAC over respiration at state 3 were measured in mitochondria isolated from rat hearts at various postnatal ages. There was a 5-fold increase in the AAC activity from… CONTINUE READING
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