Expression of synaptotagmin VIII in rat kidney.

  title={Expression of synaptotagmin VIII in rat kidney.},
  author={Bellamkonda K Kishore and James B. Wade and Kristel Schorr and Takeaki Inoue and B{\'e}atrice Mandon and Mark A. Knepper},
  journal={American journal of physiology. Renal physiology},
  volume={275 1},
The synaptotagmins are a family of integral membrane proteins proposed to function as regulators of both exocytosis and endocytosis. Here, we have used immunochemical techniques and RT-PCR to assess sites of renal expression of synaptotagmin VIII. A polyclonal antibody was raised to a synthetic peptide corresponding to the carboxy-terminal 21 amino acids of mouse synaptotagmin VIII. On immunoblots of membrane fractions from renal cortex and medulla (and in several other tissues), the antibody… CONTINUE READING


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