Expression of survivin and bax/bcl-2 in peroxisome proliferator activated receptor-gamma ligands induces apoptosis on human myeloid leukemia cells in vitro.

Abstract

The present study was undertaken to investigate the mechanisms of peroxisome proliferator activated receptor-gamma (PPAR-gamma) ligand-induced apoptosis on human myeloid leukemia K562 and HL-60 cell lines. The results revealed that both 15-deoxy-delta(12,14)-prostaglandin J2 (15d-PGJ2) and troglitazone (TGZ) have significant anti-proliferation- and… (More)

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@article{Liu2005ExpressionOS, title={Expression of survivin and bax/bcl-2 in peroxisome proliferator activated receptor-gamma ligands induces apoptosis on human myeloid leukemia cells in vitro.}, author={J. J. Liu and Rong-rong Huang and D. J. Lin and J. Peng and X. Y. Wu and Qian Lin and X. L. Pan and Y. Q. Song and M. H. Zhang and M. Hou and F. Chen}, journal={Annals of oncology : official journal of the European Society for Medical Oncology}, year={2005}, volume={16 3}, pages={455-9} }