Expression of surface markers on peripheral CD4+CD25high T cells in patients with atopic asthma: role of inhaled corticosteroid.

@article{Zhang2008ExpressionOS,
  title={Expression of surface markers on peripheral CD4+CD25high T cells in patients with atopic asthma: role of inhaled corticosteroid.},
  author={Qian Zhang and Fen-hong Qian and Hua Liu and Lin-fu Zhou and Mao Huang and Xi-long Zhang and Kai-sheng Yin},
  journal={Chinese medical journal},
  year={2008},
  volume={121 3},
  pages={205-12}
}
BACKGROUND CD4(+)CD25(+) regulatory T cells (Tregs) mediate immune suppression through cell-cell contact with surface molecules, particularly cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR), and transforming growth factor beta (TGF-beta), but little is known about the exact role of Tregs in the pathogenesis of asthma. This study sought to characterize the expression of surface markers on peripheral blood… CONTINUE READING

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