Expression of substrate-specific transporters encoded by Plasmodium falciparum in Xenopus laevis oocytes.

@article{Penny1998ExpressionOS,
  title={Expression of substrate-specific transporters encoded by Plasmodium falciparum in Xenopus laevis oocytes.},
  author={Jeffrey I Penny and Susan T Hall and Charles J Woodrow and Graeme J. M. Cowan and Annette M. Gero and Sanjeev Krishna},
  journal={Molecular and biochemical parasitology},
  year={1998},
  volume={93 1},
  pages={81-9}
}
When the malarial parasite Plasmodium falciparum multiplies in erythrocytes it dramatically increases uptake of essential metabolic precursors (nucleosides, nucleobases and glucose) and export of lactic acid by undefined mechanisms. The first evidence is provided here, by a detailed study in Xenopus laevis oocytes, that several specific nutrient transporters are the product of P. falciparum genes. We report the expression of nucleoside, nucleobase, hexose and monocarboxylate transport systems… CONTINUE READING

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