Expression of stable hepatitis B viral polymerase associated with GRP94 in E. coli

Abstract

 We here presented evidence that a 94-kDa glucose-regulated protein (GRP94) was associated with hepatitis B viral (HBV) polymerase in the human liver cell HepG2 and this association could be applied even in Escherichia coli. We investigated the role of GRP94 in the expression and stabilization of HBV polymerase in Escherichia coli by coexpression of the two… (More)
DOI: 10.1007/s007050070092

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