Expression of soluble human interleukin-2 receptor alpha-chain in Escherichia coli.

Abstract

A soluble, biologically active form of IL-2R alpha known as delta MST and consisting of the 178 N-terminal amino acid residues of the mature protein was directly expressed in the cytoplasm and the periplasm of Escherichia coli. Because it was not glycosylated, the E. coli protein was substantially less heterogeneous than delta MST expressed in insect cells… (More)

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@article{Dracheva1995ExpressionOS, title={Expression of soluble human interleukin-2 receptor alpha-chain in Escherichia coli.}, author={Svetlana Dracheva and Rocco Palermo and Gary Powers and Deanne Waugh}, journal={Protein expression and purification}, year={1995}, volume={6 6}, pages={737-47} }