Expression of smooth muscle cell markers and co-activators in calcified aortic valves.

Abstract

AIMS Similar risk factors and mediators are involved in calcific aortic stenosis (CAS) and atherosclerosis. Since normal valves harbour a low percentage of smooth muscle cells (SMCs), we hypothesize that the SMC phenotype participates in the pathogenesis of CAS. METHOD AND RESULTS We analysed 12 normal and 22 calcified aortic valves for SMC markers and… (More)
DOI: 10.1093/eurheartj/eht547

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Cite this paper

@article{Latif2015ExpressionOS, title={Expression of smooth muscle cell markers and co-activators in calcified aortic valves.}, author={Najma Latif and Padmini Sarathchandra and Adrian H Chester and Magdi Habib Yacoub}, journal={European heart journal}, year={2015}, volume={36 21}, pages={1335-45} }