Expression of smooth muscle and extracellular matrix proteins in relation to airway function in asthma.

@article{Slats2008ExpressionOS,
  title={Expression of smooth muscle and extracellular matrix proteins in relation to airway function in asthma.},
  author={Annelies M Slats and Kirsten Janssen and Annemarie A M van Schadewijk and Dirk T van der Plas and Robert Schot and Joost G van den Aardweg and Johan C. de Jongste and Pieter S Hiemstra and Thais Mauad and Klaus Friedrich Rabe and Peter J. Sterk},
  journal={The Journal of allergy and clinical immunology},
  year={2008},
  volume={121 5},
  pages={1196-202}
}
BACKGROUND Smooth muscle content is increased within the airway wall in patients with asthma and is likely to play a role in airway hyperresponsiveness. However, smooth muscle cells express several contractile and structural proteins, and each of these proteins may influence airway function distinctly. OBJECTIVE We examined the expression of contractile and structural proteins of smooth muscle cells, as well as extracellular matrix proteins, in bronchial biopsies of patients with asthma, and… CONTINUE READING

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