Expression of serum miR-200a, miR-200b, and miR-200c as candidate biomarkers in epithelial ovarian cancer and their association with clinicopathological features.

@article{Zuberi2015ExpressionOS,
  title={Expression of serum miR-200a, miR-200b, and miR-200c as candidate biomarkers in epithelial ovarian cancer and their association with clinicopathological features.},
  author={Mariyam Zuberi and Rashid Mir and Juganta Das and Imteyaz Ahmad and Jamsheed Javid and Prasant Singh Yadav and Mirza Masroor and Syed Ishraque Ahmad and Prakash Chander Ray and Anita Saxena},
  journal={Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico},
  year={2015},
  volume={17 10},
  pages={779-87}
}
BACKGROUND MicroRNAs (miRs) have been implicated in the etiology of various human cancers. The aim of this study was to investigate the association of the expression of three members--miR 200a, miR 200b, and miR 200c belonging to the miR-200 family with clinicopathological characteristics and their impact on the progression of epithelial ovarian cancer (EOC). MATERIALS AND METHODS Total RNA from serum was isolated by Trizol method, polyadenylated, and reverse transcribed into cDNA. Expression… CONTINUE READING
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